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Test ID 5362 Endomyocardial Biopsy

Useful For

Evaluation of:

-Cardiac allograft rejection

-Cardiomyopathies

-Myocarditis

-Idiopathic arrhythmias

-Idiopathic chest pain

-Anthracycline cardiotoxicity

-Secondary heart disease (amyloidosis, sarcoidosis, hemochromatosis, storage diseases, and neoplastic diseases)

Method Name

Light Microscopy

Includes hematoxylin-and-eosin, Gomori's iron, and sulfated alcian blue stains.

Electron microscopy, immunoperoxidase, and immunofluorescence are available upon special request. For special studies, call BEFORE the biopsy is performed.

Reporting Name

Endomyocardial Bx

Specimen Type

Tissue

Container/Tube: Sterile container with 10% neutral buffered formalin, Trump's solution, or tissue embedded in paraffin

Specimen Volume: Entire specimen

Collection Instructions: For the evaluation of adriamycin cardiotoxicity, specimens should be fixed in glutaraldehyde or Trump's solution. These specimens will be evaluated by transmission electron microscopy at an additional charge.

Additional Information: The clinical differential diagnoses and the name and phone number of the pathologist or cardiologist involved with the case are required.

Specimen Stability Information

Specimen Type Temperature Time
Tissue Ambient (preferred)
  Refrigerated 

Clinical Information

Endomyocardial biopsies may be indicated to evaluate a variety of cardiac disorders. The procedure is performed using a device inserted through the jugular, subclavian, or femoral vein.

Reference Values

Abnormalities will be compared to reported reference values.

Cautions

Either wet tissue fixed in 10% neutral buffered formalin or Trump's solution or slides and paraffin blocks may be submitted.

 

Electron microscopy is generally only performed for the evaluation of adriamycin cardiotoxicity and storage diseases. For the evaluation of adriamycin cardiotoxicity, specimens should be fixed in glutaraldehyde or Trump's solution.

 

Clinical diagnosis must be submitted with the specimen.

 

Not useful for distinguishing between alcoholic cardiomyopathy and idiopathic dilated cardiomyopathy.

Day(s) Performed

Monday through Friday

Report Available

2 days

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

88325

NY State Approved

Yes