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HelpTest ID 60937 Myogenin, Immunostain Without Interpretation
Useful For
Maker of skeletal muscle differentiation
Method Name
Immunohistochemistry
Reporting Name
Myogenin IHC, no interpSpecimen Type
TissueSpecimen Type: Tissue
Container/Tube: Immunostain Technical Only Envelope (Supply T693)
Preferred: Formalin-fixed, paraffin-embedded (FFPE) tissue block
Acceptable: 2 unstained positively charged glass slides (25 x 75 x 1 mm) per test ordered; sections 4 microns thick
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Ambient (preferred) | |
| Refrigerated | ||
Clinical Information
Myogenin is a member of a family of myogenic regulatory genes which include MyoD, myf5, and MRF4. These genes encode a set of transcription factors which are essential for muscle development. Expression of myogenin is restricted to cells showing skeletal muscle differentiation. Myogenin is found in the majority of rhabdomyosarcomas and Wilms tumors, and is absent in Ewing sarcoma and mature skeletal muscle.
Cautions
No significant cautionary statements
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
88342-TC, primary
88341-TC, if additional IHC