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Test ID 60937 Myogenin, Immunostain Without Interpretation

Useful For

Maker of skeletal muscle differentiation

Method Name

Immunohistochemistry

Reporting Name

Myogenin IHC, no interp

Specimen Type

Tissue

Specimen Type: Tissue

Container/Tube: Immunostain Technical Only Envelope (Supply T693)

Preferred: Formalin-fixed, paraffin-embedded (FFPE) tissue block

Acceptable: 2 unstained positively charged glass slides (25 x 75 x 1 mm) per test ordered; sections 4 microns thick

Specimen Stability Information

Specimen Type Temperature Time
Tissue Ambient (preferred)
  Refrigerated 

Clinical Information

Myogenin is a member of a family of myogenic regulatory genes which include MyoD, myf5, and MRF4. These genes encode a set of transcription factors which are essential for muscle development. Expression of myogenin is restricted to cells showing skeletal muscle differentiation. Myogenin is found in the majority of rhabdomyosarcomas and Wilms tumors, and is absent in Ewing sarcoma and mature skeletal muscle.

Cautions

No significant cautionary statements

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

88342-TC, primary

88341-TC, if additional IHC

NY State Approved

Yes