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HelpTest ID 60983 Wilms Tumor (WT-1), Immunostain Without Interpretation
Useful For
An aid in the identification of Wilms tumor
Method Name
Immunohistochemistry
Reporting Name
Wilm's Tumor (WT-1) IHC, no interpSpecimen Type
TissueSpecimen Type: Tissue
Container/Tube: Immunostain Technical Only Envelope (Supply T693)
Preferred: Formalin-fixed, paraffin-embedded (FFPE) tissue block
Acceptable: 2 unstained positively charged glass slides (25 x 75 x 1 mm) per test ordered; sections 4 microns thick.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Ambient (preferred) | |
| Refrigerated | ||
Clinical Information
Wilms tumor-1 (WT-1) protein is a transcription factor that acts as a tumor suppressor gene. WT-1 is involved in differentiation of certain tissues such as mesothelium and the urogenital system. It is also expressed in Wilms tumor, a kidney tumor found in children. In normal tissues, it is expressed in kidney, a subset of hematopoietic cells, Sertoli cells in the testis, granulosa cells in the ovary, and decidual cells of the uterus.
Cautions
No significant cautionary statements.
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
88342-TC, primary
88341-TC, if additional IHC