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HelpTest ID 64720 Lymphoid Enhancer-Binding Factor 1(LEF1), Immunostain Without Interpretation
Useful For
Differentiating cancers of B-cell origin
Method Name
Immunohistochemistry
Reporting Name
LEF1 IHC, no interpSpecimen Type
TissueSpecimen Type: Tissue
Container/Tube: Immunostain Technical Only Envelope (T693)
Preferred: Formalin-fixed, paraffin-embedded (FFPE) tissue block
Acceptable: 2 unstained positively charged glass slides (25 x 75 x 1 mm) per test ordered; sections 4-microns thick.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Ambient (preferred) | |
| Refrigerated | ||
Clinical Information
Lymphoid enhancer-binding factor 1 (LEF1) is a transcription factor that participates in the activation of genes within the Wnt signaling pathway. LEF1 is expressed by inactive T cells and a subset of B cells.
Cautions
No significant cautionary statements.
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
88342 TC, primary
88341 TC, if addt'l IHC