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Test ID 7AC4 7AC4, Bile Acid Synthesis, Serum

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)


Specimen Required


Patient Preparation:

1. Fasting: 12 hours, required; Fasting morning specimen is preferred.

2. Patient should not be taking bile acid sequestrants for 24 hours prior to collection or statins for 5 days prior to collection.

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge and aliquot 1 mL of serum into a plastic vial.

2. Send specimen frozen.


Reporting Name

7AC4, Bile Acid Synthesis, S

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 90 days
  Refrigerated  72 hours
  Ambient  24 hours

Report Available

5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
7AC4 7AC4, Bile Acid Synthesis, S 94866-1

 

Result ID Test Result Name Result LOINC Value
65504 7AC4, Bile Acid Synthesis, S 94866-1

Forms

If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen

Useful For

Screening for bile acid malabsorption in patients with irritable bowel syndrome with diarrhea

Testing Algorithm

For more information see Ordering Guide: Bile Acid-Associated Tests.

Day(s) Performed

Monday, Thursday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82542

Specimen Minimum Volume

0.5 mL

Reference Values

≥18 years: 2.5-63.2 ng/mL

Reference values have not been established for patients who are <18 years of age.