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Test ID ADMB ADAMTS13 Inhibitor Bethesda Titer, Plasma

Method Name

Only orderable as a reflex. For more information see ADAMP / ADAMTS13 Activity with Reflex Inhibitor Profile, Plasma.

 

Fluorescence Resonance Energy Transfer (FRET)


Specimen Required


Only orderable as a reflex. For more information see ADAMP / ADAMTS13 Activity with Reflex Inhibitor Profile, Plasma.

 

Specimen Type: Platelet-poor plasma

Patient Preparation:

Fasting: 8 hours, preferred but not required

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Polypropylene plastic vials

Specimen Volume: 2 mL in 2 plastic vials, each containing 1 mL

Collection Instructions:

1. Specimen must be collected prior to factor replacement therapy.

2. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.

3. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.

4. Aliquot plasma (1 mL per aliquot) into 2 separate plastic vials leaving 0.25 mL in the bottom of centrifuged vial.

5. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or ideally, at -40° C or below.

Specimen Stability Information: Frozen 2 years

Additional Information:

1. A double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. Each coagulation assay requested should have its own vial.


Reporting Name

ADAMTS13 Inhibitor Titer, P

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ADMB ADAMTS13 Inhibitor Titer, P 40824-5

 

Result ID Test Result Name Result LOINC Value
620817 ADAMTS13 Inhibitor Titer 40824-5

Useful For

Assisting with the diagnosis of congenital, immune or acquired thrombotic thrombocytopenic purpura as a part of a profile

Day(s) Performed

Monday through Friday, Sunday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

85335

Specimen Minimum Volume

2 mL

Reference Values

Only orderable as a reflex. For more information see ADAMP / ADAMTS13 Activity with Reflex Inhibitor Profile, Plasma.

 

<0.5 BU