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Test ID ADMBU ADAMTS13 Inhibitor Bethesda Titer, Plasma


Ordering Guidance


 



Specimen Required


Only orderable as part of a profile. For more information see ADM13 / ADAMTS13 Activity and Inhibitor Profile, Plasma.

 

Patient Preparation: Fasting preferred

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vials

Specimen Volume: 2 mL in 2 plastic vials each containing 1 mL

Collection Instructions:

1. Specimen must be collected prior to replacement therapy.

2. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.

3. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.

4. Aliquot plasma (1 mL per aliquot) into 2 separate plastic vials, leaving 0.25 mL in the bottom of centrifuged vial.

5. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or, ideally, below -40° C.

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. If priority specimen, mark request form, give reason, and request a call-back.

3. Each coagulation assay requested should have its own vial.


Useful For

Detecting and quantifying the presence and titer of ADAMTS-13 inhibitor to assist with the diagnosis of congenital or acquired thrombotic thrombocytopenic purpura as a part of a profile

Method Name

Only orderable as part of a profile. For more information see ADM13 / ADAMTS13 Activity and Inhibitor Profile, Plasma.

 

Fluorescence Resonance Energy Transfer (FRET)

Reporting Name

ADAMTS13 Inhibitor Bethesda Titer

Specimen Type

Plasma Na Cit

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Reference Values

Only orderable as part of a profile. For more information see ADM13 / ADAMTS13 Activity and Inhibitor Profile, Plasma.

 

<0.4 BU

Day(s) Performed

Monday through Friday, Sunday

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

85335

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ADMBU ADAMTS13 Inhibitor Bethesda Titer 40824-5

 

Result ID Test Result Name Result LOINC Value
61214 ADAMTS13 Inhibitor Bethesda Titer 40824-5