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Test ID APIVC Aldosterone, Inferior Vena Cava, Plasma

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)


Specimen Required


Patient Preparation: Spironolactone (Aldactone) should be discontinued for 4 to 6 weeks before specimen collection. The plasma renin activity cannot be interpreted if the patient is being treated with spironolactone.

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.6 mL Plasma

Collection Instructions:

1. See Renin-Aldosterone Studies for detailed instructions.

2. The recommended collection time is 8 a.m., after the patient is active for approximately 2 hours. Try to collect the specimen as close to that time as possible and no later than 10 a.m.

3. Centrifuge and aliquot plasma into a plastic vial.


Reporting Name

Aldosterone, IVC, P

Specimen Type

Plasma EDTA

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Frozen (preferred) 30 days
  Refrigerated  28 days
  Ambient  4 days

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
APIVC Aldosterone, IVC, P 1763-2

 

Result ID Test Result Name Result LOINC Value
65425 Aldosterone, IVC, P 1763-2

Useful For

Investigation using inferior vena cava plasma specimen for:

-Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia)

-Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome)

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82088

Specimen Minimum Volume

Plasma:1 mL

Reference Values

No established reference values.