Test ID C341Q Complement C3 and C4 with Anti-C1q Antibodies, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
Reporting Name
C3 and C4 with Anti-C1q, IgG, SSpecimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 21 days |
Report Available
2 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| C341Q | C3 and C4 with Anti-C1q, IgG, S | 107555-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| C3 | Complement C3, S | 4485-9 |
| C4 | Complement C4, S | 4498-2 |
| AC1Q | Anti-C1q Antibodies, IgG, S | 44702-9 |
Useful For
Evaluating patients with suspected anti-C1q vasculitis
Predicting renal involvement in patients with systemic lupus erythematosus
Day(s) Performed
C3, C4: Monday through Friday
AC1Q: Wednesday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86160 x2
83520
Specimen Minimum Volume
0.9 mL
Reference Values
C3:
75-175 mg/dL
C4:
14-40 mg/dL
AC1Q:
<20 U/mL (Negative)
20-39 U/mL (Weak Positive)
40-80 U/mL (Moderate Positive)
>80 U/mL (Strong Positive)
Method Name
AC1Q: Enzyme-Linked Immunosorbent Assay (ELISA)
C3, C4: Nephelometry
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| C3 | Complement C3, S | Yes | Yes |
| C4 | Complement C4, S | Yes | Yes |
| AC1Q | Anti-C1q Antibodies, IgG, S | Yes | Yes |