Sign in →

Test ID CBC CBC with Differential, Blood

Useful For

A screening tool to confirm a hematologic disorder, to establish or rule out a diagnosis, to detect an unsuspected hematologic disorder, or to monitor effects of radiation or chemotherapy

 

These counts are used as clinical guides in the diagnosis or monitoring of many diseases

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
DIFFR Morphology Eval (special Smear) No No

Testing Algorithm

For Mayo patients:

A morphology evaluation is performed at an additional charge when the automated 5-part differential is invalid and/or when abnormal results are identified upon microscopic examination.

 

A consultant evaluation is performed at an additional charge when pathologist expertise is needed for clinically significant diagnosis.

 

For Mayo Medical Laboratories patients:

An approval will be requested before the morphologic evaluation is ordered due to the additional charge.

Method Name

RF/DC (Radio Frequency/Direct Current) Detection Method/Hydro Dynamic Focusing (DC Detection), Flow Cytometry Method (Using a Semiconductor Laser), and Sodium Lauryl Sulfate (SLS) Hemoglobin Method

Reporting Name

CBC with Differential, B

Specimen Type

Whole Blood EDTA

Specimen must arrive within 24 hours of draw.

 

Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 24 hours
  Ambient  24 hours

Clinical Information

RBCs, WBCs, and platelets are produced in the bone marrow and released into the peripheral blood. The primary function of the RBC is to deliver oxygen to tissues. WBCs are key components of the immune system. Platelets play a vital role in blood clotting.

 

Mean corpuscular volume (MCV) is a measure of the size of the average RBC. Anemias are characterized as microcytic (MCV <80), macrocytic (MCV >100), or normocytic. The red cell distribution width (RDW) is a measure of the degree of variation in RBC size (anisocytosis). RDW may be helpful in distinguishing between some anemias. For example, iron deficiency anemia is characterized by a high RDW, while thalassemia is characterized by a low RDW.

Reference Values

RED BLOOD CELL COUNT (RBC)

Males:

Birth: 3.90-5.50 x 10(12)/L

1-7 days: 3.90-6.00 x 10(12)/L

8-14 days: 3.60-6.00 x 10(12)/L

15 days-1 month: 3.00-5.50 x 10(12)/L

2-5 months: 3.10-4.50 x 10(12)/L

6 months-1 year: 3.70-6.00 x 10(12)/L

2 years: 4.10-5.10 x 10(12)/L

3-5 years: 4.10-5.30 x 10(12)/L

6-11 years: 4.20-5.10 x 10(12)/L

12-15 years: 4.40-5.50 x 10(12)/L

Adults: 4.32-5.72 x 10(12)/L

Females:

Birth: 3.90-5.50 x 10(12)/L

1-7 days: 3.90-6.00 x 10(12)/L

8-14 days: 3.60-6.00 x 10(12)/L

15 days-1 month: 3.00-5.50 x 10(12)/L 

2-5 months: 3.10-4.50 x 10(12)/L

6 months-1 year: 3.70-6.00 x 10(12)/L

2 years: 4.10-5.10 x 10(12)/L 

3-5 years: 4.10-5.20 x 10(12)/L

6-11 years: 4.10-5.30 x 10(12)/L

12-15 years: 4.10-5.20 x 10(12)/L

Adults: 3.90-5.03 x 10(12)/L

 

HEMOGLOBIN

Males:

Birth-7 days: 13.5-22.0 g/dL

8-14 days: 12.5-21.0 g/dL

15 days-1 month: 10.0-20.0 g/dL

2-5 months: 10.0-14.0 g/dL

6 months-1 year: 10.5-13.5 g/dL

2 years: 11.0-14.0 g/dL

3-5 years: 11.0-14.5 g/dL

6-11 years: 12.0-14.0 g/dL

12-15 years: 12.8-16.0 g/dL

Adults: 13.5-17.5 g/dL

Females:

Birth-7 days: 13.5-22.0 g/dL

8-14 days: 12.5-21.0 g/dL

15 days-1 month: 10.0-20.0 g/dL

2-5 months: 10.0-14.0 g/dL

6 months-1 year: 10.5-13.5 g/dL

2 years: 11.0-14.0 g/dL 

3-5 years: 11.8-14.7 g/dL

6-11 years: 12.0-14.5 g/dL

12-15 years: 12.2-14.8 g/dL

Adults: 12.0-15.5 g/dL

 

HEMATOCRIT

Males:

Birth-7 days: 42.0-60.0%

8-14 days: 39.0-60.0%

15 days-1 month: 31.0-55.0%

2-5 months: 28.0-42.0%

6 months-1 year: 33.0-40.0%

2 years: 33.0-42.0%

3-5 years: 33.0-43.0%

6-11 years: 35.8-42.4%

12-15 years: 37.3-47.3%

Adults: 38.8-50.0%

Females:

Birth-7 days: 42.0-60.0%

8-14 days: 39.0-60.0%

15 days-1 month: 31.0-55.0% 

2-5 months: 28.0-42.0%

6 months-1 year: 33.0-40.0%

2 years: 33.0-42.0%

3-5 years: 35.0-44.0%

6-11 years: 35.7-43.0%

12-15 years: 36.3-43.4%

Adults: 34.9-44.5%

 

MEAN CORPUSCULAR VOLUME (MCV)

Males:

Birth: 98.0-120.0 fL

1-7 days: 88.0-120.0 fL

8-14 days: 86.0-120.0 fL

15 days-1 month: 85.0-110.0 fL 

2-5 months: 77.0-110.0 fL

6 months-5 years: 74.0-89.0 fL

6-11 years: 76.5-90.6 fL

12-15 years: 81.4-91.9 fL

Adults: 81.2-95.1 fL

Females:

Birth: 98.0-120.0 fL

1-7 days: 88.0-120.0 fL

8-14 days: 86.0-120.0 fL

15 days-1 month: 85.0-110.0 fL 

2-5 months: 77.0-110.0 fL

6 months-5 years: 74.0-89.0 fL

6-11 years: 78.5-90.4 fL

12-15 years: 79.9-92.3 fL

Adults: 81.6-98.3 fL

 

RED CELL DISTRIBUTION WIDTH (RDW)

Males:

<2 years: not established 

2 years: 12.0-14.5%

3-5 years: 12.0-14.0%

6-11 years: 12.0-14.0%

12-15 years: 11.6-13.8%

Adults: 11.8-15.6%

Females:

<2 years: not established

2 years: 12.0-14.5%

3-5 years: 12.0-14.0%

6-11 years: 11.6-13.4%

12-15 years: 11.2-13.5%

Adults: 11.9-15.5%

 

WHITE BLOOD CELL COUNT (WBC)

Males:

Birth: 9.0-30.0 x 10(9)/L

1-7 days: 9.4-34.0 x 10(9)/L

8-14 days: 5.0-21.0 x 10(9)/L

15 days-1 month: 5.0-20.0 x 10(9)/L

2-5 months: 5.0-15.0 x 10(9)/L

6 months-1 year: 6.0-11.0 x 10(9)/L

2 years: 5.0-12.0 x 10(9)/L

3-5 years: 4.0-12.0 x 10(9)/L

6-11 years: 3.4-9.5 x 10(9)/L

12-15 years: 3.6-9.1 x 10(9)/L

Adults: 3.5-10.5 x 10(9)/L

Females:

Birth: 9.0-30.0 x 10(9)/L

1-7 days: 9.4-34.0 x 10(9)/L

8-14 days: 5.0-21.0 x 10(9)/L

15 days-1 month: 5.0-20.0 x 10(9)/L

2-5 months: 5.0-15.0 x 10(9)/L

6 months-1 year: 6.0-11.0 x 10(9)/L

2 years: 5.0-12.0 x 10(9)/L

3-5 years: 4.0-12.0 x 10(9)/L

6-11 years: 3.4-10.8 x 10(9)/L

12-15 years: 4.1-8.9 x 10(9)/L

Adults: 3.5-10.5 x 10(9)/L

 

PLATELETS

Birth-5 months: 150-350 x 10(9)/L

≥6 months: 150-450 x 10(9)/L

 

NEUTROPHILS

Birth: 6.00-26.00 x 10(9)/L

1-7 days: 1.50-10.00 x 10(9)/L

8-14 days: 1.00-9.50 x 10(9)/L

15 days-1 month: 1.00-9.00 x 10(9)/L

2-5 months: 1.00-8.50 x 10(9)/L

6 months-5 years: 1.50-8.50 x 10(9)/L

6-11 years: 1.50-8.50 x 10(9)/L    

12-15 years: 1.80-8.00 x 10(9)/L

Adults: 1.70-7.00 x 10(9)/L

 

LYMPHOCYTES

Birth: 2.00-11.00 x 10(9)/L

1-14 days: 2.00-17.00 x 10(9)/L 

15 days-1 month: 2.50-16.50 x 10(9)/L

2-5 months: 4.00-13.50 x 10(9)/L

6 months-11 months: 4.00-10.50 x 10(9)/L

1-5 years: 1.50-7.00 x 10(9)/L

6-11 years: 1.50-6.50 x 10(9)/L

12-15 years: 1.20-5.20 x 10(9)/L

Adults: 0.90-2.90 x 10(9)/L

 

MONOCYTES

Birth-14 days: 0.40-1.80 x 10(9)/L

15 days-11 months: 0.05-1.10 x 10(9)/L

1-15 years: 0.00-0.80 x 10(9)/L

Adults: 0.30-0.90 x 10(9)/L

 

EOSINOPHILS

Birth-5 months: 0.02-0.85 x 10(9)/L

6 months-11 months: 0.05-0.70 x 10(9)/L

1-5 years: 0.00-0.65 x 10(9)/L

6-15 years: 0.00-0.50 x 10(9)/L

Adults: 0.05-0.50 x 10(9)/L

 

BASOPHILS

Birth-5 months: 0.00-0.60 x 10(9)/L

6 months-15 years: 0.00-0.20 x 10(9)/L 

≥16 years: 0.00-0.30 x 10(9)/L

Cautions

Questionable results are detected by in-house checking criteria based on quantitative and qualitative parameters.

 

Defined laboratory instrument and/or patient flagging criteria may trigger peripheral blood smear review resulting in consultant readout of hematologic abnormalities.

Day(s) Performed

Monday through Sunday; Continuously

Report Available

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

85025-CBC

85007-Differential (if appropriate)

85060-Hematopathology consultation (if appropriate)

NY State Approved

Yes