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HelpTest ID DHPVA Human Papillomavirus (HPV) Type 16, Droplet Digital PCR, Blood
Method Name
Droplet Digital Polymerase Chain Reaction (ddPCR)
Ordering Guidance
This test should be ordered to monitor circulating cell free DNA for the high-risk human papillomavirus (HPV)-16 genotype in patients with a previous diagnosis of HPV-16. If the intent is a pre-diagnostic screen for which the genotype is not previously known, order DHPVR / Human Papillomavirus (HPV) Type 16 with Type 18/31/33/35 Reflex, Droplet Digital PCR, Blood which can detect and quantify circulating cell free DNA from 5 high-risk HPV genotypes: HPV-16, -18, -31, -33 and -35.
For routine cervical cancer screening, order VHPV / Human Papillomavirus (HPV) Vaginal Detection with Genotyping for High-Risk Types by PCR.
Specimen Required
Supplies: Streck Tan Top Tube Kit (T715)
Container/Tube: Streck Cell-Free DNA blood collection kit
Specimen Volume: Two 10-mL Streck Cell-Free DNA blood collection tubes
Additional Information: Only blood collected in Streck Cell-Free DNA tubes will be accepted for analysis.
Reporting Name
HPV-16, cfDNA, Quant ddPCR, BSpecimen Type
Whole bloodSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Ambient (preferred) | 7 days |
| Refrigerated | 7 days |
Report Available
5 to 10 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DHPVA | HPV-16, cfDNA, Quant ddPCR, B | 112586-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 622874 | HPV-16 ddPCR Result | 61372-9 |
| 622875 | HPV-16 ddPCR Quant | 112587-1 |
Useful For
Aid in the monitoring of human papillomavirus (HPV)-16 associated disease
Disease monitoring after treatment of HPV-related cancer and/or post-treatment surveillance as a prognostic indicator of cancer recurrence
This test should not be used to screen asymptomatic patients.
Day(s) Performed
Varies
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
87799
Specimen Minimum Volume
One 10 mL Streck Cell-Free DNA blood collection tube
Reference Values
Not detected