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HelpTest ID DSGAB Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL Serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reporting Name
Desmoglein 1 and 3, SerumSpecimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 14 days |
Report Available
1 to 10 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DSGAB | Desmoglein 1 and 3, Serum | 94335-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 606818 | DSG 1 | 94336-5 |
| 606819 | DSG 3 | 94337-3 |
Useful For
Preferred screening test for patients suspected of having an autoimmune blistering disorder of the skin or mucous membranes (pemphigus)
Aiding in the diagnosis of pemphigus
Testing Algorithm
For information see Autoimmune Blistering Disease Diagnostic Algorithm.
Day(s) Performed
Varies
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83516 x 2
Specimen Minimum Volume
Serum: 0.5 mL
Reference Values
Desmoglein 1:
<20 RU/mL (Negative)
≥20 RU/mL (Positive)
Desmoglein 3:
<20 RU/mL (Negative)
≥20 RU/mL (Positive)