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Test ID DSS Drug Screen, Prescription/Over the Counter, Serum


Ordering Guidance


For chain-of-custody testing, order DSSX / Drug Screen, Prescription/Over the Counter, Chain of Custody, Serum.



Specimen Required


Collection Container/Tube: Red top (serum gel/SST tubes are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2.75 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.


Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen. 

Secondary ID

8421

Useful For

Detection and identification of prescription or over the counter drugs frequently found in drug overdose or used with a suicidal intent

 

Qualitatively identifying drugs present in the specimen; quantification of identified drugs, when available, may be performed upon client request

 

This test is not intended for therapeutic drug monitoring or compliance testing.

 

This test is not intended for use in employment-related testing.

 

This test is not useful for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, amphetamine type stimulants.

Special Instructions

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS)

Reporting Name

Drug Screen, Prescription/OTC, S

Specimen Type

Serum Red

Specimen Minimum Volume

1.1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  3 hours

Clinical Information

This test looks for a broad spectrum of prescription and over-the-counter (OTC) drugs. It is designed to detect drugs that have toxic effects, as well as known antidotes or active therapies that a clinician can initiate to treat the toxic effect. The test is intended to help physicians manage an apparent overdose or intoxicated patient, or to determine if a specific set of symptoms might be due to the presence of drugs. This test is not appropriate for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, and amphetamine type stimulants.

 

Drugs of toxic significance that are not detected by this test are: digoxin, lithium, and many drugs of abuse or illicit drugs, some benzodiazepines, and some opioids.

 

For more information see Emergency/Overdose for detection limits for drugs detected in this test.

Reference Values

Drugs detected are presumptive. Additional testing may be required to confirm the presence of any drugs detected.

Cautions

Specimens collected in serum gel tubes are not acceptable, as the drug/analyte can absorb on the gel and lead to falsely decreased concentrations.

Day(s) Performed

Monday through Sunday

Report Available

3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80307

NY State Approved

Yes