Test ID DSS Drug Screen, Prescription/OTC, Serum
Useful For
Detection and identification of prescription or over the counter drugs frequently found in drug overdose or used with a suicidal intent
This test is designed to qualitatively identify drugs present in the specimen; quantification of identified drugs, when available, may be performed upon client request
Special Instructions
Method Name
Gas Chromatography-Mass Spectrometry (GC-MS)
Reporting Name
Drug Screen, Prescription/OTC, SSpecimen Type
Serum RedContainer/Tube: Red top
Specimen Volume: 5.25 mL
Additional Information:
1. See Prescription and Over-the-Counter (OTC) Drug Screens in Special Instructions.
2. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order COCH / Chain-of-Custody Processing.
3. This test is not appropriate for drugs of abuse/illicit drug testing. Cocaine will not be detected in this assay.
4. Not intended for use in employment-related testing.
5. This test is not appropriate for assessment of therapeutic compliance.
Forms: Chain-of-Custody Request Form is included in the Chain-of-Custody Kit (T282). A copy of this form is also available at http://www.mayomedicallaboratories.com/it-mmfiles/chain-of-custody-request-form.pdf.
Specimen Minimum Volume
2.1 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum Red | Refrigerated (preferred) | 14 days |
Frozen | 14 days | |
Ambient | 3 hours |
Clinical Information
This test looks for a broad spectrum of prescription and over-the-counter (OTC) drugs. It is designed to detect drugs that have toxic effects, as well as known antidotes or active therapies that a clinician can initiate to treat the toxic effect. The test is intended to help physicians manage an apparent overdose or intoxicated patient, or to determine if a specific set of symptoms might be due to the presence of drugs. The test is not designed to screen for intermittent use or illicit drugs.
Drugs of toxic significance that are not detected by this test are: digoxin, lithium, and many drugs of abuse/illicit drugs, some benzodiazepines, and some opioids.
See Prescription and Over-the-Counter (OTC) Drug Screens in Special Instructions.
Reference Values
Drug detection
Cautions
Not intended for therapeutic compliance testing.
Not intended for use in employment-related testing.
Not intended for drugs of abuse/illicit drug testing.
Not all drugs can be quantitatively extracted from the specimen, so accurate quantification may not be possible, and many do not have reference ranges.
For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. See COCH / Chain-of-Custody-Processing.
Day(s) Performed
Monday through Sunday; Varies
Report Available
2 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80304
G0479 (if appropriate)