Test ID DSSX Drug Screen, Prescription/OTC, Chain of Custody, Serum
Useful For
Detection and identification of prescription or over the counter drugs frequently found in drug overdose or used with a suicidal intent
This test is designed to qualitatively identify drugs present in the specimen; quantification of identified drugs, when available, may be performed upon client request.
Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was under the control of personnel involved with testing the specimen at all times; this control implies that the opportunity for specimen tampering would be limited.
Additional Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
COCH | Chain of Custody Processing | No | Yes |
Method Name
Gas Chromatography-Mass Spectrometry (GC-MS)
Reporting Name
Drug Scrn, Prescription/OTC, CoC, SSpecimen Type
Serum RedContainer/Tube: Red top; Chain-of-Custody Kit (T282) contains the specimen seals and documentation required
Preferred: One 10-mL red
Acceptable: One 5-mL red
Specimen Volume: 5.25 mL
Collection Instructions: Collect specimen, centrifuge within 2 hours of collection and aliquot serum, cap and seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Additional Information:
1. Chain-of-Custody Kit (T282) containing the specimen seals and documentation are required.
2. See Table 1 in Prescription and Over-the-Counter (OTC) Drug Screens in Special Instructions.
3. This test is not appropriate for drugs of abuse/illicit drug testing. Cocaine will not be detected in this assay.
Forms: Chain-of-Custody Request Form is included in the Chain-of-Custody Kit (T282). A copy of this form is also available at http://www.mayomedicallaboratories.com/it-mmfiles/chain-of-custody-request-form.pdf.
Specimen Minimum Volume
2.1 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum Red | Refrigerated (preferred) | 14 days |
Frozen | 14 days | |
Ambient | 3 hours |
Clinical Information
This test looks for a broad spectrum of prescription and over-the-counter (OTC) drugs. It is designed to detect drugs that have toxic effects, as well as known antidotes or active therapies that a clinician can initiate to treat the toxic effect. The test is intended to help physicians manage an apparent overdose or intoxicated patient, to determine if a specific set of symptoms might be due to the presence of drugs, or to evaluate a patient who might be abusing these drugs intermittently. The test is not designed to screen for intermittent use of illicit drugs.
Drugs of toxic significance that are not detected by this test are: digoxin, lithium, and many drugs of abuse/illicit drugs, some benzodiazepines, and most opiates.
See Prescription and Over-the-Counter (OTC) Drug Screens Table 1 in Special Instructions.
Chain of custody is a record of the disposition of a specimen to document who collected it, who handled it, and who performed the analysis. When a specimen is submitted in this manner, analysis will be performed in such a way that it will withstand regular court scrutiny.
Reference Values
Drug detection
Cautions
Not intended for therapeutic compliance testing.
Not intended for use in employment-related testing.
Not intended for drugs of abuse/illicit drug testing.
Not all drugs can be quantitatively extracted from the specimen, so accurate quantification may not be possible, and many do not have reference ranges.
Day(s) Performed
Monday through Sunday; Varies
Report Available
2 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80304
G0479 (if appropriate)