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Test ID EMAT Endomysial Antibodies, IgA, Titer, Serum


Specimen Required


Only orderable as a reflex. For more information see EMA / Endomysial Antibodies, IgA, Serum.


Secondary ID

65091

Useful For

Confirmation of a positive IgA-endomysial antibodies result

Testing Algorithm

This field is updated on 01/20/2025 for testing purpose.

Method Name

Only orderable as a reflex. For more information see EMA / Endomysial Antibodies, IgA, Serum.

 

Indirect Immunofluorescence Assay (IFA)

Reporting Name

EMA Titer, S (IgA)

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Clinical Information

Circulating IgA endomysial antibodies are present in 70% to 80% of patients with dermatitis herpetiformis or celiac disease, and in nearly all such patients who have high grade gluten-sensitive enteropathy and are not adhering to a gluten-free diet.

 

Because of the high specificity of endomysial antibodies for celiac disease, the test may obviate the need for multiple small bowel biopsies to verify the diagnosis. This may be particularly advantageous in the pediatric population, including the evaluation of children with failure to thrive.

Reference Values

Only orderable as a reflex. For more information see EMA / Endomysial Antibodies, IgA, Serum.

 

Negative

Cautions

A negative result (absence of circulating IgA-endomysial antibodies) does not exclude the diagnosis of dermatitis herpetiformis or celiac disease.

 

Patients with mild gluten-sensitive enteropathy may have a negative result.

Day(s) Performed

Monday through Friday

Report Available

2 days. This field is updated on 01/20/2025 for testing purpose.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86231

This field is updated on 01/20/2025 for testing purpose.

NY State Approved

Yes