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Test ID FACYS Acyclovir, Plasma

Method Name

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)


Specimen Required


***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***

 

Collection Container/Tube: Lavender top or pink top (EDTA) (Plasma gel/PST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Plasma

Collections Instructions:

1. Centrifuge and aliquot 1 mL of plasma into a plastic vial.

2. Send refrigerated.


Reporting Name

Acyclovir, Plasma

Specimen Type

Plasma EDTA

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Refrigerated (preferred) 30 days
  Frozen  120 days
  Ambient  30 days

Report Available

9 to 11 days

Performing Laboratory

NMS Labs

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FACYS Acyclovir, Plasma 9416-9

 

Result ID Test Result Name Result LOINC Value
Z3531 Acyclovir Not Provided

Day(s) Performed

Monday through Sunday

Test Classification

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80299

Specimen Minimum Volume

Plasma: 0.5 mL

Reference Values

Reporting limit determined each analysis.

 

For using Acyclovir:

Usual therapeutic range (vs. Genital Herpes) during chronic oral daily divided dosages of 1200-2400 mg:

Peak: 0.40-2.0 mcg/mL plasma

Trough: 0.14-1.2 mcg/mL plasma

 

For using Valacyclovir as a metabolite:

Mean steady-state (±1 SD) peak plasma levels following a 500 mg twice daily regimen

of Valacyclovir:

2.0-4.0 mcg Acyclovir/mL