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Test ID FAPPL Atypical Pneumonia Panel

Profile Information

Test ID Reporting Name Available Separately Always Performed
CHPA1 Chlamydia and Chlamydophila Ab Pnl No Yes
FLEGA Legionella Pneumophila Ab (Total) No Yes
FMPAG M. Pneumoniae Ab IgG No Yes
FMPAM M. Pneumoniae Ab IgM No Yes

Method Name

Immunofluorescence Assay (IFA)/Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Atypical Pneumonia Panel

Specimen Type

Serum

Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 3 mL of serum refrigerated in a plastic vial.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  4 days

Reference Values

Chlamydia and Chlamydophila Antibody Panel 3 (IgG, IgA, IgM)

C.Trachomatis, C.Pneumoniae, C.Psittaci  (IgG, IgA, IgM )

Reference Range:   IgG < 1:64

                             IgA < 1:16

                             IgM < 1:10

 

The immunofluorescent detection of specific antibodies to Chlamydia trachomatis, Chlamydophila pneumoniae, and C. psittaci may be complicated by crossreactive antibodies, non-specific antibody stimulation, or past exposure to more than one of these organisms. IgM titers of 1:10 or greater are indicative of recent infection; however, IgM antibody is very crossreactive, often demonstrating titers to multiple organisms. Any IgG titer may indicate past exposure to that particular organism. Infection by a particular organism typically yields IgG titers that are higher than antibody titers to non-infecting organisms. IgA titers may help to identify the infecting organism when crossreactive IgG is present.  IgA is typically present at low titers during primary infection, but may be elevated in recurrent exposures or in chronic infection.

  

Legionella Pneumophila Antibodies (Total)

  L. pneumophila (serogroup 1) and (serogroups 2-6, 8)

   

Reference Ranges:  <1:16

 

Total antibodies to Legionella pneumophila serogroup 1 and 6 additional L. pneumophila serogroups (2, 3, 4, 5, 6, 8) are measured using a polyvalent conjugate.

 

The antibody response to Legionella may be detected 4 days to 6 weeks after exposure and may remain elevated for months or years.  Thus, a fourfold or greater rise in titer is required to confirm a diagnosis of current infection. Serologic testing does not usually allow definitive differentiation of Legionella serogroups.

 

Mycoplasma Pneumoniae Antibody (IgG)

 

Reference Range:    ≤0.90

 

Interpretive criteria;

    ≤0.90    Negative

   0.91-1.09  Equivocal

    ≥1.10    Positive

 

A positive result indicates that the patient has antibody to Mycoplasma. It does not differentiate between an active or past infection. The clinical diagnosis must be interpreted in conjunction with the clinical signs and symptoms of the patient.

 

Mycoplasma Pneumoniae Antibody (IgM)

 

Reference Range:  <770 U/mL

 

Interpretive criteria:

      <770 U/mL       Negative

      770-950 U/mL   Low positive

       >950 U/mL      Positive

 

Day(s) Performed

Monday through Saturday; Varies

Report Available

1 - 4 days

Performing Laboratory

Focus Diagnositics, Inc.

Test Classification

These assays were developed and their performance characteristics have been determined by Focus Diagnostics. They have not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.

CPT Code Information

86631 x6 Chlamydia

86632 x3 Chlamydia, IgM

86713 x2 Legionella

86738 x2 Mycoplasma

NY State Approved

Yes