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HelpTest ID FCAH6 CAH Pediatric Profile 6, Comprehensive Screen (Androstenedione, Specific S, Cortisol, DHEA, DOC, 17-OH-Prenenolone, Progesterone, 17-OH-Progesterone, Testosterone)
Method Name
Radioimmunoassay (RIA)
High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)
Reporting Name
CAH Profile 6Specimen Type
SerumDraw blood in a plain, red-top tube(s). Spin down and separate within 1 hour of collection and send 3.5 mL of serum frozen in plastic vial. Specimens drawn in serum gel tube(s) must be poured off into a plastic screw cap vial before freezing.
Specimen Minimum Volume
2 mL
NOTE: Minimum volume does not allow for
repeat analysis.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen | 30 days |
Reference Values
Androstenedione
Units: ng/dL
Age Range
Premature (26-28w) Day 4 63 - 935
Premature (31-35w) Day 4 50 - 449
Full Term (1-7 days) <10 - 279
Levels decrease rapidly to a range of <52 ng/dL after one week.
1-11m <10 - 37
Androstenedione gradually decreases during the first six months to prepubertal levels.
Prepubertal Children <10-17
Adult Males 44 - 186
Adult Females 28 - 230
Females Postmenopausal <10-93
Females
Tanner Stages Age (years) Range
1 <9.2 <10-17
2 9.2-13.7 <10-72
3 10.0-14.4 50-170
4 10.7-15.6 47-208
5 11.8-18.6 50-224
Males
Tanner Stages Age (years) Range
1 <9.8 <10-17
2 9.8-14.5 <10-33
3 10.7-15.4 17-72
4 11.8-16.2 15-115
5 12.8-17.3 33-192
Cortisol
Units: ug/dL
Age Range
Premature (26-28w) Day 4 1.0 - 11
Premature (31-35w) Day 4 2.5 - 9.1
Full Term Day 3 1.7 - 14
Full Term Day 7 2.0 - 11
31d - 11m 2.8 - 23
12m - 15y (8:00 AM) 3 .0 - 21
Adults
8:00 AM 8.0 - 19
4:00 PM 4.0 - 11
Deoxycorticosterone (DOC)
Units: ng/dL
Age Range
Premature (26 - 28w) Day 4 20 - 105
Premature (34 - 36w) Day 4 28 - 78
Newborn: Levels are markedly elevated at birth and decrease rapidly during the first week to the range of 7 - 49 as found in older infants.
1 - 11m 7 - 49
Prepubertal Children 2 - 34
Pubertal Children
and Adults 8:00 AM 2 – 19
Dehydroepiandrosterone (DHEA)
Units: ng/dL
Age Range
1-5 yrs <68
6-7 yrs <111
8-10 yrs <186
11-12 yrs <202
13-14 yrs <319
15-16 yrs 39-481
17-19 yrs 40-491
20-49 yrs 31-701
≥ 50 yrs 21-402
11-Desoxycortisol
Units: ng/dL
Age Range
Premature (26-28w) Day 4 110 - 1376
Premature (31-35w) Day 4 48 - 579
Newborn Day 3 13 - 147
1 - 11m <10 - 156
Prepubertal 8:00 AM 20 - 155
Pubertal Children and
Adults 8:00 AM 12 - 158
17-OH Pregnenolone
Units: ng/dL
Age Range
Premature (26-28w) Day 4 375 - 3559
Premature (31-35w) Day 4 64 - 2380
3 Days 10 - 829
1 - 5m 36 - 763
6 - 11m 42 - 540
12 - 23m 14 - 207
24m - 5y 10 - 103
6 - 9y 10 - 186
Pubertal 44 - 235
Adults 53 - 357
Progesterone
Units: ng/dL
Males
Age Range
1-16y <10-15
Adults <10-11
Females
Age Range
1-10y <10-26
11y <10-255
12y <10-856
13y <10-693
14y <10-1204
15y <10-1076
16y <10-1294
Adult
Cycle Days Range
1-6 <10-17
7-12 <10-135
13-15 <10-1563
16-28 <10-2555
Post Menopausal <10
Note: Luteal progesterone peaked from 350 to 3750 ng/dL
on days ranging from 17 to 23.
17-Alpha-Hydroxyprogesterone
Units: ng/dL
Age Range
Premature (26-28w) Day 4 124 - 841
Premature (31-35w) Day 4 26 - 568
Full-Term Day 3 <78
Males: Levels increase after the first week to peak values ranging from 40 - 200 between 30 and 60 days. Values then decline to a prepubertal value of <91 before one year.
Prepubertal <91
Adult Males 27-199
Females
1 - 11m 13-106
Prepubertal <91
Adult Females
Follicular 15-70
Luteal 35-290
Females
Tanner Stages Age (years) Range
1 <9.2 <83
2 9.2-13.7 11-98
3 10.0-14.4 11-155
4 10.7-15.6 18-230
5 11.8-18.6 20-265
Males
Tanner Stages Age (years) Range
1 <9.8 <91
2 9.8-14.5 <116
3 10.7-15.4 10-138
4 11.8-16.2 29-180
5 12.8-17.3 24-175
Testosterone, Serum (Total)
Units: ng/dL
Age Range
Males
Premature (26-28w) Day 4 59 - 125
Premature (31-35w) Day 4 37 - 198
Newborns 75 - 400
1 - 7m: Levels decrease rapidly the first week to 20 - 50, then increase to 60 - 400 between 20 - 60 days. Levels then decline to prepubertal range levels of <2.5 - 10 by seven months.
Females
Premature (26 - 28w) Day 4 5 - 16
Premature (31 - 35w) Day 4 5 - 22
Newborns 20 - 64
1 - 7m: Levels decrease during the first month to less than 10 and remain there until puberty.
Prepubertal Males and Females <2.5 - 10
Adult Males >18 years 348 - 1197
Adult Females
Premenopausal: 10 - 55
Postmenopausal: 7 - 40
Males
Tanner Stage Age (years) Male
1 <9.8 <2.5 - 10
2 9.8 – 14.5 18 - 150
3 10.7 – 15.4 100 - 320
4 11.8 – 16.2 200 - 620
5 12.8 – 17.3 350 - 970
Females
Tanner Stage Age (years) Female
1 <9.2 <2.5 - 10
2 9.2 - 13.7 7 - 28
3 10.0 - 14.4 15 - 35
4 10.7 - 15.6 13 - 32
5 11.8 - 18.6 20 - 38
Day(s) Performed
Monday, Wednesday
Report Available
4 - 8 daysPerforming Laboratory
Esoterix EndocrinologyCPT Code Information
82633/DOC
82634/Specific S
82157/Androstenedione
82533/Cortisol
82626/DHEA
84143/17-OH-Pregnenolone
84144/Progesterone
83498/17-OH-Progesterone
84403/Testosterone