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Test ID FFAG4 Filaria IgG4 Antibody, ELISA

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Filaria IgG4 Antibody

Specimen Type

Serum

Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 0.2 mL serum refrigerated in a plastic vial.

Specimen Minimum Volume

0.1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  7 days

Reference Values

Reference Range: <1:50

 

Interpretive Criteria:

 

<1:50         Negative

1.50-3.00    Equivocal

>3.00         Positive

 

This assay detects Filaria IgG4 associated with infections caused by the major filarial parasites, including Dirofilaria immitis, Wuchereria brancrofti, Brugia malayi, and Onchocerca volvulus. Detection of IgG4 subclass antibody offers enhanced specificity without sacrifice of sensitivity. Chronic filarial infections manifesting as elephantiasis may not show a significant IgG4 response, and cannot be ruled out by this assay. Equivocal results may represent cross-reactive antibodies induced by infection with other nematodes.

Day(s) Performed

Wednesday

Report Available

1 - 8 days

Performing Laboratory

Focus Diagnositics, Inc.

Test Classification

This test was developed and its performance characteristics have been determined by Focus Diagnostics. Performance characteristics refer to the analytical performance of the test.

CPT Code Information

86682

NY State Approved

Yes