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Test ID FFAPL Febrile Antibodies Panel

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FRMFG RMSF IgG Titer No No
FRMFM RMSF IgM Titer No No
FRTG R. Typhi IgG Titer No No
FRTM R. Typhi IgM Titer No No
FBRAG Brucella Agglutination No No

Testing Algorithm

If RMSF IgG is Detected, then FRMFG RMSF IgG Titer will be performed at an additional charge.

If RMSF IgM is Detected, then FRMFM RMSF IgM Titer will be performed at an additional charge.

If R. Typhi IgG is Detected, then FRTG R. Typhi IgG Titer will be performed at an additional charge.

If R. Typhi IgM is Detected, then FRTM R. Typhi IgM Titer will be performed at an additional charge.

If Brucella IgM is ≥1.10, then FBRAG Brucella Agglutination will be performed at an additional charge.

Method Name

Immunofluorescence Assay (IFA)

Enzyme Immunoassay (EIA)

Reporting Name

Febrile Antibodies Panel

Specimen Type

Serum

Draw blood in a plain, red-top tube(s) or serum gel tube(s). Spin down and send 3 mL of serum refrigerated.

Specimen Minimum Volume

0.8 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  7 days

Reference Values

Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers

 Reference Range: Not Detected

 

Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers

 Reference Range: Not Detected

 

Salmonella Antibodies, EIA

 Reference Range: Not Detected

 

Antibodies to Salmonella flagellar (H) and somatic (O) antigens typically peak 3 – 5 weeks after infection. A positive results in this assay is equivalent to a titer of ≥1:160 by tube agglutination (Widal). Results should not be considered as diagnostic unless confirmed by culture.

 

Brucella Antibodies (IgG, IgM), EIA with Reflex to Agglutination

 Reference Range: <0.80

 

 Interpretive Criteria:

            <0.80 Antibody not detected

            0.80 – 1.09 Equivocal

            ≥ 1.10 Antibody detected

 

Acute brucellosis is characterized by the appearanceof Brucella-specific IgM within the first week of infection, followed by the appearance of Brucella-specific IgG after the second week. Levels of both IgM and IgG decline slowly over several months in conjunction with recovery. Persistence of high IgG levels with declining or absent IgM suggests chronic infection or relapse.

 

Day(s) Performed

Varies; Monday through Friday

Report Available

1 - 4 days

Performing Laboratory

Focus Diagnositics, Inc.

CPT Code Information

86622/x2 Brucella

86757/x4 Rickettsia

86768/x5 Salmonella

86757/ each Rickettsia titer, if appropriate

86622/Brucella agglutination, if appropriate

NY State Approved

Yes