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Test ID FFES Estradiol Free, Serum (includes Estradiol and SHBG)

Method Name

Mass Spectrometry

Reporting Name

Free Estradiol

Specimen Type

Serum

Draw blood in a plain, red-top tube or serum gel tube. Spin down, pour off into plastic vial within 1 hour of collection, and send 3 mL serum frozen.

Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 180 days
  Ambient  5 days
  Refrigerated  5 days

Reference Values

Free Estradiol, Percent

Reference Ranges (%)

      Age                        Range

Adult Males                   1.7 - 5.4

Adult Females               1.6 - 3.6

 

Free Estradiol, Serum

Reference Ranges (pg/mL)

      Age                        Range

Adult Males                   0.2 - 1.5

Adult Females               0.6 - 7.1

 

Sex Hormone Binding Globulin (SHBG), Serum

Reference Ranges (nmol/L)

      Age                                    Range

 1 - 23m                                    60 - 252

Prepubertal (24m - 8y)                72 - 220

Pubertal

  Males                                     16 - 100

  Females                                  36 - 125

Adult Males                               20 - 60

Adult Females

   Premenopausal                       40 - 120

   Postmenopausal                     28 - 112

 

Estradiol, Serum

Reference Ranges (pg/mL)

 

       Age                       Range

Newborn                        Levels are markedly elevated at birth and fall rapidly during the first week to prepubertal values of <15

Males <6m                    Levels increase to 10 - 32 between 30 and 60 days, hen decline to prepubertal levels of <15 by six months.

Females <1y                 Levels increase to 5.0 - 50 between 30 and 60 days, then decline to prepubertal levels of <15 during the first year.

Prepubertal                    <15

Adult Males                   8.0 - 35

Adult Females

 Follicular                      30 - 100

 Luteal                          70 - 300

 Postmenopausal           <15

 

  

Test Performed By:   Esoterix Endocrinology

                                        4301 Lost Hills Road

                                        Calabasas Hills, CA 91301

Day(s) Performed

Varies

Report Available

7 - 10 days

Performing Laboratory

Esoterix Endocrinology

Test Classification

ASR - Analyte Specific Reagent for Sex Hormone Binding Globulin (SHBG), Serum This test was developed and its performance characteristics determined by Esoterix. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance is not necessary. This test is used for clinical purposes. It should not be regarded as investigational or for research. This laboratory is regulated under the Clinical Laboratory Improvement Amendment (CLIA) of 1988 as qualified to perform high complexity clinical testing.

CPT Code Information

82670/Estradiol

84270/Sex Hormone binding globulin

84999/Unlisted chemistry procedure

NY State Approved

Yes