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Test ID FGENC Fungal Culture, Spinal Fluid

Useful For

Diagnosing fungal infections from cerebrospinal fluid (separate tests are available for other specimen sites)

Method Name

Conventional agar culture technique with identification by macroscopy and microscopic morphology, nucleic acid hybridization probes, D2 rDNA gene sequencing, real-time polymerase chain reaction (rtPCR), or MALDI-TOF mass spectrometry. Dimorphic pathogen identification is confirmed using molecular methods (ie, D2 rDNA gene sequencing, rtPCR or MALDI-TOF mass spectrometry).

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)

Reporting Name

Fungal Culture, CSF

Specimen Type

CSF

Only orderable as a reflex. For more information see LFACX / Crytpococcus Antigen with Reflex, LFA, Spinal Fluid.

 

 Specimen should arrive within 24 hours of collection.

                   

Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 1 mL

Specimen Minimum Volume

0.1 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Clinical Information

Many fungi in the environment cause disease in severely compromised human hosts. Accordingly, the range of potential pathogenic fungi has increased as the number of immunosuppressed individuals (eg, persons with AIDS, patients receiving chemotherapy, or transplant rejection therapy) has increased.

                                  

Few fungal diseases can be diagnosed clinically; many are diagnosed by isolating and identifying the infecting fungus in the clinical laboratory.

Reference Values

Negative

If positive, fungus will be identified.

Cautions

For optimal recovery of organisms, sufficient specimen should be transported within 24 hours of collection.

           

Fungi can be pathogens, colonizers, or contaminants. Correlation of the patient clinical condition with culture results is necessary for optimal patient care.

Day(s) Performed

Monday through Sunday; Continuously

Report Available

24 days/Positive cultures reported when detected. Preliminary negative report generated at 7 and 14 days.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87102-Fungal culture, routine

87106-Yeast identification panel C (if appropriate)

87106-Yeast identification panel D (if appropriate)

87106-Id MALDI-TOF Mass Spec Yeast (if appropriate)

87107-Id MALDI-TOF Mass Spec Fungi (if appropriate)

87107-Fungal identification panel A (if appropriate)        

87107-Fungal identification panel B (if appropriate)

87107-Yeast identification panel A (if appropriate)

87107-Yeast identification panel B (if appropriate)

87150-Identification rapid PCR Coccidioides (if appropriate)

87150 x 2-Identification Histoplasma/Blastomyces, PCR (if appropriate)

87150-Microbial probe, fungus identification (if appropriate)       

87153-D2 fungal sequencing identification (if appropriate)

87176-Tissue processing (if appropriate)

NY State Approved

Yes