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HelpTest ID FGHTL Ghrelin Total, Plasma
Specimen Required
Patient preparation: Patient should be fasting 10 - 12 hours prior to collection of specimen. Patient should not be on any medications or supplements that may influence: Cholecystokinin (CCK), Glucose, Growth Hormone, Insulin and/or Somatostatin levels, if possible for at least 48 hours prior to specimen collection.
Specimen Type: GI Plasma
Container/Tube: Special tube containing G.I. Preservative (MCL supply number T125).
Specimen Volume: 3-5 mL
Collection Instructions: Draw 10 mL of blood in special tube containing G.I. Preservative (MCL supply number T125). Specimen should be separated in refrigerated centrifuge as soon as possible and send 3-5 mL plasma frozen. Ship frozen.
Method Name
EIA/ELISA
Reporting Name
Ghrelin Total, PlasmaSpecimen Type
GI PlasmaSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| GI Plasma | Frozen | 180 days |
Clinical Information
Ghrelin is a novel 28 amino acid peptide derived by post-translational processes from a preproghrelin consisting of 117 residues, secreted by the stomach with specific receptors in the brain involved in appetite regulation. It conveys information to the brain thereby increasing appetite, food intake and body weight and influences the release of growth hormone. Ghrelin is a growth hormone-releasing peptide which acts as an endogenous ligand of the growth hormone secretagogue receptors (GHS-Rs). Ghrelin levels are inversely correlated with body weight and are higher during weight loss.
Reference Values
GHRELIN (Total): pg/mL
(Plasma)
Adult Reference Range(s)
Normal weight/control subjects: 520 - 700 pg/mL
Obese subjects prior to diet: 340 - 450 pg/mL
Levels:
8:00 am - 12:00 pm: Up to 420 pg/mL
6:00pm: Up to 480 pg/mL
Obese subjects post induced weight loss: 450 - 600 pg/mL
Levels:
8:00 am - 12:00 pm: Up to 575 pg/mL
6:00 pm: Up to 600 pg/mL
Obese subjects post gastric-bypass surgery: Up to 120 pg/mL
Day(s) Performed
Monday through Friday
Report Available
9 to 11 daysPerforming Laboratory
Inter Science InstituteTest Classification
This test was performed using a kit that has not been cleared or approved by the FDA and is designated as research use only. The analytic performance characteristics of this test have been determined by Inter Science Institute. This test is not intended for diagnosis or patient management decisions without confirmation by other medically established means.CPT Code Information
83520