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HelpTest ID FPD2U Prostaglandin D2 (PG D2), Urine
Specimen Required
Patient Preparation: Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen. Specimen must be frozen within 30 minutes of collection.
Specimen Type: Urine
Submission Container/Tube: Plastic, 10-mL tube (T068)
Specimen Volume: 10 mL
Collection Instructions:
1. Collect random urine (NO preservative).
3. Freeze immediately and send specimen frozen in the plastic, 10-mL urine tube (T068)
Note: 24 hours urine collection is not acceptable.
Secondary ID
75366Method Name
Direct EIA/ELISA
Reporting Name
Prostaglandin D2 (PG D2), USpecimen Type
UrineSpecimen Minimum Volume
5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | |
|---|---|---|---|
| Urine | Frozen | 180 days |
Clinical Information
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2 and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.
Reference Values
Up to 175 ng/g Creatinine
Day(s) Performed
Upon receipt
Report Available
10 to 14 daysPerforming Laboratory
Inter Science InstituteTest Classification
This test was performed using a kit that has not been cleared or approved by the FDA and is designated as research use only. The analytic performance characteristics of this test have been determined by Inter Science Institute. This test is not intended for diagnosis or patient management decisions without confirmation by other medically established means.CPT Code Information
84150