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HelpTest ID FSERO SeroNeg RAdx3 Profile
Specimen Required
Collection Container/Tube: 10 mL Red
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Acceptable: SST
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 3 mL of serum refrigerated in a plastic vial.
Secondary ID
75621Method Name
ELISA
Reporting Name
SeroNeg RAdx3 ProfileSpecimen Type
SerumSpecimen Minimum Volume
3 mL (volume does NOT allow for repeat testing)
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 60 days | |
| Ambient | 7 days |
Clinical Information
SeroNeg RAdx3 is a diagnostic and prognostic panel for Rheumatoid Arthritis designed to complement traditional RF and Anti-CCP testing. This profile, consisting of 14-3-3 eta protein, Anti -CEP-1 Ab and Anti-Sa Ab, enhances the diagnosis of established or early RA (in individuals seronegative for RF and Anti-CCP Ab) and also helps predict disease severity. Decrease in 14-3-3eta and/or Anti-Sa Ab with treatment is associated with less radiographic progression. The presence of Anti-CEP1 and Anti-CCP Antibodies suggests the imminent progression of pre-clinical RA into clinical RA
Reference Values
Interpretation for:
14.3.3 ETA, Rheum. Arthritis:
Reference Range: <0.20 ng/mL
Negative: <0.20 ng/mL
Weak Positive: 0.20-0.39 ng/mL
Moderate Positive: 0.40-0.79 ng/mL
Strong Positive: >0.79 ng/mL
Interpretation for:
Anti-CEP-1 Ab, IgG and Anti-Sa Ab, IgG:
Reference Range: <20
Negative: <20 units
Weak Positive: 20-39 units
Moderate Positive: 40-80 units
Strong Positive: >80 units
Day(s) Performed
Monday through Friday
Report Available
9 to 14 daysPerforming Laboratory
Esoterix EndocrinologyTest Classification
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.CPT Code Information
83520
83516 x2