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HelpTest ID FSINE Sinemet , Serum/Plasma
Method Name
High-Performance Liquid Chromatography (HPLC)
Reporting Name
SinemetSpecimen Type
VariesSubmit only 1 of the following specimens:
Serum
Draw blood in a plain, red-top tube(s). (Serum gel tube is not acceptable.) Spin down and send 2 mL of serum frozen in a preservative-free plastic vial. Specimen must be frozen immediately or results will be compromised.
Plasma
Draw blood in a lavender-top or pink-top (EDTA) tube(s). (Plasma gel tube is not acceptable.) Spin down and send 2 mL of EDTA plasma frozen in a preservative-free plastic vial. Specimen must be frozen immediately or results will be compromised.
Specimen Minimum Volume
0.7 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Frozen | 30 days |
Reference Values
Reporting limit determined each analysis.
Levodopa
Synonym(s): Sinemet Constituent
Carbidopa
Synonyms(s): Sinemet Constituent
Following a single oral dose of 100 mg Levodopa and 25 mg Carbidopa (conventional Sinemet tablet): Approximately 0.3 mcg Levodopa/mL and 0.05 mcg Carbidopa/mL plasma at 1 hour post dose. Average steady-state trough plasma levels in elderly patients following a regimen of Sinemet CR (50 mg Carbidopa and 200 mg Levodopa sustained release tablets) three times daily:
0.16 mcg Levodopa/mL
0.07 mcg Carbidopa/mL
Day(s) Performed
Tuesday
Report Available
3 daysPerforming Laboratory
NMS LabsCPT Code Information
80375