Home
HelpTest ID GRP Cyclic AMP, Urinary Excretion
Useful For
The differential diagnosis of hypercalcemia
An adjunct to serum parathyroid hormone measurements, especially in the diagnosis of parathyroid hormone resistance states, such as pseudohypoparathyroidism
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CREAS | Creatinine, S | Yes, (order CREAZ) | Yes |
| CAMP | Cyclic Amp, Urinary Excretion | No | Yes |
| CACR | Creatinine, U | Yes, (order RCTUR) | Yes |
Method Name
CREAS, CACR: Enzymatic Colorimetric Assay
CAMP: High-Performance Liquid Chromatography (HPLC)
Reporting Name
Cyclic Amp, Urinary ExcretionSpecimen Type
SerumUrine
Serum and urine are required. Serum must be drawn at time of urine collection.
Specimen Type: Serum
Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Specimen Volume: 1 mL
Collection Instructions: Label specimen as serum.
Specimen Type: Urine
Container/Tube: 60 mL urine container (Supply T313)
Specimen Volume: 14 mL
Collection Instructions:
1. Collect a random urine specimen.
2. Label specimen as urine.
Specimen Minimum Volume
Serum: 0.5 mL/Urine: 5.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 90 days | |
| Urine | Frozen | 14 days |
Clinical Information
Cyclic AMP functions as an intracellular "second messenger" regulating the activity of intracellular enzymes or proteins in response to a variety of hormones (eg, parathyroid hormone).
Urinary cyclic AMP is elevated in about 85% of patients with hyperparathyroidism.
Reference Values
1.3-3.7 nmol/dL of glomerular filtrate
Cautions
Parathyroid suppression (hypoparathyroidism) does not lower urinary cyclic AMP excretion to definitely subnormal values.
Day(s) Performed
Wednesday; 9 a.m.
Report Available
2 daysPerforming Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
See Individual Test IDsCPT Code Information
82030