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Test ID HITIG Heparin-PF4 IgG Antibody, Serum

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)


Specimen Required


Patient Preparation:

Fasting: 8 hours, preferred but not required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.

Specimen Stability Information: Frozen (preferred) 2 years/Refrigerate 7 days


Reporting Name

Heparin-PF4 IgG Ab (HIT), S

Specimen Type

Serum Red

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen (preferred)
  Refrigerated  7 days

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HITIG Heparin-PF4 IgG Ab (HIT), S 73818-7

 

Result ID Test Result Name Result LOINC Value
46915 HIT ELISA 73818-7
21468 Heparin Inhibition 73817-9
21469 HIT Interpretation 73819-5
21470 HIT Comment 73816-1

Useful For

Detection of IgG antibodies directed against heparin/platelet factor 4 complexes that are implicated in the pathogenesis of immune-mediated type II heparin-induced thrombocytopenia, spontaneous heparin platelet-factor 4 IgG antibody, and thrombocytopenia and thrombosis occurring after SARS-CoV2 adenovirus vector vaccine

Day(s) Performed

Monday through Sunday

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86022

Specimen Minimum Volume

0.5 mL

Reference Values

HIT ELISA:

<0.400

 

HIT Interpretation:

Negative