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HelpTest ID HSMP Hepatosplenomegaly Panel, Plasma
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Ordering Guidance
This test should not be used for monitoring of patients with confirmed diagnoses. If testing requested is for monitoring purposes, see:
CTXP / Cerebrotendinous Xanthomatosis, Plasma
GPSYP / Glucopsychosine, Plasma
OXNP / Oxysterols, Plasma
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Green top (sodium heparin, lithium heparin), yellow top (ACD B)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.3 mL
Collection Instructions:
1. Centrifuge at 4° C, if possible
2. Aliquot plasma into plastic vial. Do not disturb or transfer the buffy coat layer.
3. Send frozen
Reporting Name
Hepatosplenomegaly Panel, PSpecimen Type
PlasmaSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Frozen | 65 days |
Report Available
3 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HSMP | Hepatosplenomegaly Panel, P | 92743-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 601542 | Interpretation (HSMP) | 59462-2 |
| 601536 | Cholestane-3beta,5alpha,6beta-triol | 92755-8 |
| 601537 | 7-Ketocholesterol | 92764-0 |
| 601538 | Lyso-sphingomyelin | 92747-5 |
| 601539 | Glucopsychosine | 92750-9 |
| 601540 | 7a-hydroxy-4-cholesten-3-one | 92761-6 |
| 601541 | 7a,12a-dihydroxycholest-4-en-3-one | 92758-2 |
| 601543 | Reviewed By | 18771-6 |
Forms
If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.
Useful For
As a component to the initial evaluation of a patient presenting with hepatosplenomegaly, using plasma specimens
This test is not useful for the identification of carriers.
This test should not be used as a monitoring tool for patients with confirmed diagnoses.
Day(s) Performed
Tuesday, Thursday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542
Specimen Minimum Volume
0.25 mL
Reference Values
Cholestane -3-beta, 5-alpha, 6-beta-troil
Cutoff: ≤0.070 nmol/mL
7-Ketocholesterol
Cutoff: ≤0.100 nmol/mL
Lyso-sphingomyelin Cutoff: ≤0.100 nmol/mL
Glucopsychosine Cutoff: ≤0.003 nmol/mL
7-Alpha-hydroxy-4-cholesten-3-one Cutoff: ≤0.300 nmol/mL
7-Alpha,12-alpha-dihydroxycholest-4-en-3-one
Cutoff: ≤0.100 nmol/mL