Test ID IOD Iodine, Serum
Useful For
Determination of iodine overload
Monitoring iodine levels in individuals taking iodine-containing drugs
Special Instructions
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name
Iodine, SSpecimen Type
SerumCollection Container/Tube: Plain, royal blue-top Vacutainer plastic trace element blood collection tube (Supply T184)
Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial (Supply T173)
Specimen Volume: 1 mL
Collection Instructions:
1. Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.
2. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
3. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.
Additional Information:
1. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
2. If ordering the trace element blood collection tube from BD, order catalog #368380.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum | Refrigerated (preferred) | 21 days |
Ambient | 21 days | |
Frozen | 21 days |
Clinical Information
Iodine is an essential element that is required for thyroid hormone production. The measurement of iodine serves as an index of adequate dietary iodine intake and iodine overload, particularly from iodine-containing drugs such as amiodarone.
Reference Values
40-92 ng/mL
Cautions
There are no known analytical interferences with this procedure.
Administration of iodine-containing contrast media will yield elevated results.
Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.
High concentrations of gadolinium are known to interfere with most metals tests. If gadolinium-containing contrast media has been administered, a specimen should not be collected for 48 hours.
Day(s) Performed
Monday, Tuesday, Wednesday, Friday; 5 p.m.
Report Available
1 dayPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83018