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Test ID KETAU Ketamine and Metabolite Confirmation, Urine

Useful For

Detection and confirmation of ketamine use

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS)

Reporting Name

Ketamine Confirmation, U

Specimen Type

Urine

Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 20 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. No STATS are accepted for this procedure.

3. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order KETAX / Ketamine Confirmation, Chain of Custody, Urine.

4. Additional drug panels and specific requests are available. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700.

5. If urine creatinine is required or adulteration of the sample is suspected, the following test should be requested, ADULT / Adulterants Survey, Urine. For additional information, refer to ADULT / Adulterants Survey, Urine.

6. Submitting <20 mL will compromise our ability to perform all necessary testing.

Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Clinical Information

Ketamine has been used in the United States as an anesthetic induction agent since 1972. The drug acts by noncompetitive antagonism of the N-methyl-D-aspartate (NMDA)-type glutamate receptors.(1,2) Ketamine has become a popular street drug because of its hallucinogenic effects.(3)

 

Ketamine has a half-life of 3 to 4 hours, and is metabolized to norketamine.(3) The effects from ketamine last from 1 to 5 hours, and ketamine and/or norketamine can be detected in the urine for a period of 1 to 2 days following use.(4)

Reference Values

Negative

Cautions

A kit including all the materials necessary to complete chain-of-custody is available to ensure that the test results are appropriate for legal proceedings.

Day(s) Performed

Monday

Report Available

2 days

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80357

G0480 (if appropriate)

NY State Approved

Yes