Test ID KETAU Ketamine and Metabolite Confirmation, Urine
Useful For
Detection and confirmation of ketamine use
Method Name
Gas Chromatography-Mass Spectrometry (GC-MS)
Reporting Name
Ketamine Confirmation, USpecimen Type
UrineContainer/Tube: Plastic, 60-mL urine bottle
Specimen Volume: 20 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information:
1. No specimen substitutions.
2. No STATS are accepted for this procedure.
3. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order KETAX / Ketamine Confirmation, Chain of Custody, Urine.
4. Additional drug panels and specific requests are available. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700.
5. If urine creatinine is required or adulteration of the sample is suspected, the following test should be requested, ADULT / Adulterants Survey, Urine. For additional information, refer to ADULT / Adulterants Survey, Urine.
6. Submitting <20 mL will compromise our ability to perform all necessary testing.
Specimen Minimum Volume
5 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 14 days |
Frozen | 14 days | |
Ambient | 72 hours |
Clinical Information
Ketamine has been used in the United States as an anesthetic induction agent since 1972. The drug acts by noncompetitive antagonism of the N-methyl-D-aspartate (NMDA)-type glutamate receptors.(1,2) Ketamine has become a popular street drug because of its hallucinogenic effects.(3)
Ketamine has a half-life of 3 to 4 hours, and is metabolized to norketamine.(3) The effects from ketamine last from 1 to 5 hours, and ketamine and/or norketamine can be detected in the urine for a period of 1 to 2 days following use.(4)
Reference Values
Negative
Cautions
A kit including all the materials necessary to complete chain-of-custody is available to ensure that the test results are appropriate for legal proceedings.
Day(s) Performed
Monday
Report Available
2 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80357
G0480 (if appropriate)