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HelpTest ID KIPM Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Manual
Shipping Instructions
Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.
Necessary Information
1. Pathologist's name, address, and phone number are required.
2. Include accompanying pathology report stating the final diagnosis. If not available, a preliminary diagnosis is acceptable.
Specimen Required
Only orderable as a reflex. For more information see KI67P / Ki-67 (MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated.
Supplies: Pathology Packaging Kit (T554)
Specimen Type:
Preferred: Formalin-fixed, paraffin-embedded tissue block containing carcinoid/atypical carcinoid of the lung including metastases.
Acceptable: 2 Unstained sections on charged slides cut at 4 microns <1 month ago. Tissue on the slides should have been fixed in 10% neutral buffered formalin.
Container/Tube: Pathology Packaging Kit
Collection Instructions:
1. Submit formalin-fixed, paraffin-embedded tissue block.
2. Attach the green pathology address label included in the kit to the outside of the transport container.
Additional Information: Paraffin block will be returned with the final report.
Secondary ID
72131Useful For
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases, using a manual method
Method Name
Only orderable as a reflex. For more information see KI67P / Ki-67 (MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated.
Immunohistochemistry, Semi- Quantitation, Hot-Spot Technique
Reporting Name
Ki67 Pulmonary IHC ManualSpecimen Type
SpecialSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Special | Ambient (preferred) | |
| Refrigerated | ||
Clinical Information
Ki-67(MIB-1 clone) is a monoclonal antibody that reacts with cells undergoing DNA synthesis by binding to the Ki-67 antigen, a marker known to be expressed only in proliferating cells. By measuring the amount of tumor cells expressing Ki-67, an estimate of DNA synthesis can be determined. Studies suggest that Ki-67(MIB-1) analysis of paraffin-embedded tissue specimens may provide useful prognostic information in various tumor types.
Reference Values
Only orderable as a reflex. For more information see KI67P / Ki-67 (MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated.
Varies by tumor type; values reported from 0% to 100%
Cautions
The paraffin block analyzed must be representative of the patient's tumor.
Test results should be interpreted in the context of clinical findings and other laboratory data.
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
88360