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HelpTest ID LAGGT Granulocyte Antibodies, Serum
Useful For
The work-up of individuals having febrile, nonhemolytic transfusion reactions
The detection of individuals with autoimmune neutropenia
Method Name
Indirect Immunofluorescence
Reporting Name
Granulocyte Ab, SSpecimen Type
Serum RedContainer/Tube: Red top
Specimen Volume: 1.5 mL
Additional Information: Only pretransfusion reaction specimen is acceptable.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 30 days |
| Frozen | 365 days | |
| Ambient | 7 days |
Clinical Information
Granulocyte antibodies are induced by pregnancy or prior transfusion and are associated with febrile, nonhemolytic transfusion reactions. Patients who have been immunized by previous transfusions, pregnancies, or allografts frequently experience febrile, nonhemolytic transfusion reactions which must be distinguished from hemolysis before further transfusions can be safely administered. Granulocyte antibodies may also be present in autoimmune neutropenia.
Reference Values
Not applicable
Cautions
Not useful for diagnosis of neutropenia caused by marrow suppression by drugs or tumors
Day(s) Performed
Tuesday, Wednesday, Friday; 7:30 a.m.-5 p.m.
Report Available
7 daysPerforming Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
86021