Home
HelpTest ID LPS Lipase, Serum
Useful For
Investigating pancreatic disorders, usually pancreatitis
Method Name
Colorimetric Rate Reaction
Reporting Name
Lipase, SSpecimen Type
SerumContainer/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.5 mL
Collection Instructions:
1. Serum gel tube must be centrifuged within 2 hours of draw time.
2. Red-top tube must be centrifuged and aliquoted within 2 hours of draw time.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 90 days |
Clinical Information
Lipases are enzymes that hydrolyze glycerol esters of long-chain fatty acids and produce fatty acids and 2-acylglycerol. Bile salts and a cofactor, colipase, are required for full catalytic activity and greatest specificity. The pancreas is the primary source of serum lipase. Both lipase and colipase are synthesized in the pancreatic acinar cells and secreted by the pancreas in roughly equimolar amounts. Lipase is filtered and reabsorbed by the kidneys. Pancreatic injury results in increased serum lipase levels.
Reference Values
≥16 years: 10-73 U/L
Reference values have not been established for patients that are <16 years of age.
Cautions
Patients should be fasting before the specimen is drawn.
Collection tubes with glycerol-lubricated stoppers or tubes containing citrate, oxalate, or EDTA should not be used.
Certain drugs such as cholinergics and opiates may elevate serum lipase.
Renal disease may elevate the serum lipase.
Day(s) Performed
Monday through Sunday; Continuously
Report Available
Same day/1 dayPerforming Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
83690