Test ID MORS Morphine and Metabolite, Serum
Ordering Guidance
This test should only be ordered by healthcare professionals to monitor patients who have been prescribed morphine.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reporting Name
Morphine and metabolite, SSpecimen Type
Serum RedSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 24 hours |
Report Available
2 to 9 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MORS | Morphine and metabolite, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623447 | Morphine - Free | 11244-1 |
| 623448 | Hydromorphone - Free | 12787-8 |
Useful For
Monitoring therapeutic efficacy/compliance in serum specimens of patients who are prescribed morphine
Day(s) Performed
Tuesday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
G0480
80361 (if appropriate for select payers)
Specimen Minimum Volume
Serum: 0.5 mL
Reference Values
Therapeutic range/Metabolite information (as applicable):
Morphine: 10-80 ng/mL
Hydromorphone: 1.0-30 ng/mL when used as sole therapy; Minor metabolite of morphine
Cutoff concentrations:
Morphine: 1.0 ng/mL
Hydromorphone: 1.0 ng/mL
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)