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HelpTest ID MPCT Muscle Pathology Consultation
Useful For
Obtaining a rapid, expert opinion on unprocessed muscle specimens
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MCL4 | Muscle, Level IV Consult | No, (Bill Only) | No |
| MCRV | Muscle Consult, w/Complex Rvw of Hx | No, (Bill Only) | No |
| MCOS | Muscle Consult, Outside Slide | No, (Bill Only) | No |
| MCSP | Muscle Consult, w/Slide Prep | No, (Bill Only) | No |
| MCPRO | Muscle Consult, w/USS Prof | No, (Bill Only) | No |
| ATPS | ATPase Acid Alkaline Stain | No, (Bill Only) | No |
| CONGR | Congo Red Stain | No, (Bill Only) | No |
| OROS | Oil Red O Stain | No, (Bill Only) | No |
| PASS | Periodic Acid-Schiff Stain | No, (Bill Only) | No |
| TWSS | Trichrome Water Soluble Stain | No, (Bill Only) | No |
| ASNES | Acetate Non-specific Esterase Stain | No, (Bill Only) | No |
| ACPHS | Acid Phosphatase Stain | No, (Bill Only) | No |
| CYOXS | Cytochrome Oxidase Stain | No, (Bill Only) | No |
| NADS | NADH Dehydrogenase Stain | No, (Bill Only) | No |
| PHPHS | Phosphorylase Stain | No, (Bill Only) | No |
| SDS | Succinic Dehydrogenase Stain | No, (Bill Only) | No |
| TBATP | TB ATPase Stain | No, (Bill Only) | No |
| ALZRS | Alizarin Red Stain | No, (Bill Only) | No |
| ANS | Alpha-naphthyl Stain | No, (Bill Only) | No |
| MBS1 | IHC Initial Single Antibody Stain | No, (Bill Only) | No |
| MBS2 | IHC, Each Add'l Antibody Stain | No, (Bill Only) | No |
Testing Algorithm
When this test is ordered, 1 or more of the listed reflex tests will be performed and charged separately. The reviewing neuromuscular pathologist will determine the need for additional testing.
For all consultations, ancillary testing necessary to determine a diagnosis is ordered at the discretion of the Mayo Clinic neuromuscular pathologist. An interpretation, which includes an evaluation of the specimen and determination of a diagnosis, will be provided within a formal pathology report.
Frozen tissue for consultation: Appropriate additional stains may be performed and will be charged separately.
Note: Testing requested by the referring physician (immunostains, etc) may not be performed if deemed unnecessary by the reviewing Mayo neuromuscular pathologist. Electron microscopic studies are not performed on muscle biopsy specimens.
Special Instructions
Method Name
The evaluation of frozen muscle tissue includes a battery of enzyme histochemical stains or immunostains; other tests can be performed as indicated and will be charged separately.
Reporting Name
Muscle Pathology Consult, Frozen TsSpecimen Type
TissueFor all specimens, patient history and requests should be clearly labeled with correct patient identifiers and pathology accession/case number. Collection date and patient date of birth are required. All specimens must be labeled with specimen type. The name and phone number of the ordering physician and a brief history are essential to achieve a consultation fully relevant to the ordering physician's needs. The Muscle Histochemistry Patient Information Sheet should accompany all specimens. Failure to provide this information may delay the specimen processing significantly.
Biopsies from different sites require separate orders and separate specimen vials.
Specimen Type: Muscle biopsy tissue (frozen)
Send specimen Monday, Tuesday, or Wednesday only.
Collection Instructions: Prepare and transport specimen per instructions in Muscle Biopsy Specimen Preparation Sheet in Special Instructions.
Specimen Stability Information: Frozen
Additional Information:
1. Contact Dr. Andrew Engel (Director of the Muscle Laboratory) or Dr. Duygu Selcen (Associate Director of the Muscle Laboratory) for special problems to maximize benefit of the muscle biopsy.
2. Muscle Biopsy Shipping Kits (Supply T541) are available.
3. This test is not appropriate for inhalation-transmission diseases such as tuberculosis, Brucella, measles, and varicella zoster. This test is also not appropriate for suspected Creutzfeldt-Jacobs Disease (CJD).
Forms:
1. Muscle Histochemistry Patient Information Sheet (Supply T361) in Special Instructions.
2. If not ordering electronically, complete, print, and send the following form with the specimen:
Pathology Test Request Form (T246) (http://www.mayomedicallaboratories.com/it-mmfiles/pathology-request-form.pdf)
Specimen Minimum Volume
1.5 cm biopsy
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Frozen | |
Clinical Information
In our consultative practice, we strive to bring the customer the highest quality of diagnostic neuromuscular pathology, aiming to utilize only those ancillary tests that support the diagnosis in a cost-effective manner, and to provide a rapid turnaround time for diagnostic results.
Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Friday; Varies
Report Available
3-5 days; Note: Cases requiring additional staining and ancillary testing may require additional time.Performing Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
88305-Surgical pathology, gross and microscopic examination (if appropriate)
88321-Consultation and report on referred slides prepared elsewhere (if appropriate)
88323-Consultation and report on referred material requiring preparation of slides (if appropriate)
88323-26-Consultation and report on referred unstained slides (if appropriate)
88325-Consultation, comprehensive, with review of records and specimens, with report on referred material (if appropriate)