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HelpTest ID MYGLS Myoglobin, Serum
Useful For
Assessing muscle damage from any cause
Method Name
Latex Particle-Enhanced Immunoturbidometric Assay
Reporting Name
Myoglobin, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 14 days |
Clinical Information
Myoglobin is a heme protein found in smooth and skeletal muscles. Serum myoglobin reflects a balance between intravascular release of myoglobin from muscle and renal clearance.
Previously serum myoglobin had been advocated as a sensitive marker for early acute myocardial injury (eg, acute myocardial infarction: AMI). However, more recent studies indicate that other newer markers (eg, troponin) provide superior diagnostic utility in detecting early myocardial injury.
Elevation of serum myoglobin may occur as a result of muscle trauma, resuscitation, myopathies, AMI, shock, strenuous body activity, or decreased elimination during renal insufficiency. Extreme elevations occur in rhabdomyolysis.
Reference Values
≤90 mcg/L
Cautions
Elevation is nonspecific for acute myocardial infarction. The test is of no value in this regard in the presence of renal failure, rhabdomyolysis, extensive trauma, acute peripheral vascular occlusion, or after seizures.
Serum levels rise in renal insufficiency.
Results are unreliable in lipemic serum; specimens that cannot be cleared by ultracentrifugation will be rejected.
Day(s) Performed
Monday through Sunday, continuous
Report Available
1 dayPerforming Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
83874