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Test ID PBCRU Lead/Creatinine Ratio, Random, Urine

Useful For

Detecting clinically significant lead exposure

Profile Information

Test ID Reporting Name Available Separately Always Performed
PBCO Pb Conc No Yes
CDCR Creatinine Conc No Yes

Method Name

PBCO: Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

CDCR: Enzymatic Colorimetric Assay

Reporting Name

Lead/Creat Ratio, Random, U

Specimen Type

Urine

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 10-mL urine tube (Supply T068) or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL                                                                                       

Collection Instructions:

1. Collect a random urine specimen.

2. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.

Additional Information: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Clinical Information

Increased urine lead concentration per gram of creatinine indicates significant lead exposure. Measurement of urine lead concentration per gram of creatinine before AND after chelation therapy has been used as an indicator of significant lead exposure. An increase in lead concentration per gram of creatinine in the post chelation specimen of up to 6X the concentration in the prechelation specimen is normal.

 

Blood lead is the best clinical correlate of toxicity.

 

For additional information, see PBBD / Lead with Demographics, Blood.

Reference Values

<5 mcg/g Creatinine

Reference values apply to all ages.

Cautions

This test is not a substitute for blood lead screening.

 

High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium-or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Day(s) Performed

Monday through Friday; 7 p.m., Saturday; 2 p.m.

Report Available

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

See Individual Test IDs

CPT Code Information

83655

NY State Approved

Yes