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Test ID PK1 Pyruvate Kinase Enzyme Activity, Blood


Specimen Required


Container/Tube:

Preferred: Yellow top (ACD solution B)

Acceptable: Lavender top (EDTA)

Specimen Volume: 6 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Reporting Name

PK Enzyme Activity, B

Specimen Type

Whole Blood ACD-B

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood ACD-B Refrigerated 20 days

Report Available

1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PK1 PK Enzyme Activity, B 32552-2

 

Result ID Test Result Name Result LOINC Value
PKCL PK Enzyme Activity, B 32552-2

Forms

If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.

Useful For

Evaluation of nonspherocytic hemolytic anemia

 

Evaluation of neonatal anemia or jaundice

 

Evaluation of unexplained noninfectious hepatic failure

 

Evaluation of unexplained iron overload

 

Evaluation of unusually severe hemoglobin S trait

 

Evaluation of unusually severe glucose 6-phosphate dehydrogenase deficiency

 

Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84220

Specimen Minimum Volume

1 mL

Reference Values

≥12 months of age: 5.5-12.4 U/g Hb

 

Reference values have not been established for patients younger than 12 months.

Method Name

Kinetic Spectrophotometry (KS)