Test ID PLP Pyridoxal 5-Phosphate, Plasma
Shipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Patient Preparation:
1. Fasting-overnight (12-14 hours) (infants-collect specimen prior to next feeding). Water can be taken as needed
2. For 24 hours prior to specimen collection, patient must not take multivitamins or vitamin supplements.
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube: Green top (sodium or lithium heparin) or plasma gel separator (PST)
Submission Container/Tube: Amber vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge at 4° C within 2 hours of collection
2. Aliquot all plasma into amber vial and freeze immediately
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.
Useful For
Determining vitamin B6 status, including in persons who present with progressive nerve compression disorders, such as carpal tunnel and tarsal tunnel syndromes
Determining the overall success of a vitamin B6 supplementation program
Diagnosis and evaluation of hypophosphatasia
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Pyridoxal 5-Phosphate (PLP), PSpecimen Type
Plasma HeparinSpecimen Minimum Volume
0.75 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Heparin | Frozen | 29 days | LIGHT PROTECTED |
Reference Values
5-50 mcg/L
Day(s) Performed
Monday through Thursday, Saturday, Sunday
Report Available
1 to 4 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84207
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
PLP | Pyridoxal 5-Phosphate (PLP), P | 30552-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
4047 | Pyridoxal 5-Phosphate (PLP), P | 30552-4 |