Home
HelpTest ID PPAP Parental Sample Prep for Prenatal Microarray Testing
Useful For
Preparing parental blood samples for possible confirmation testing if an abnormality is detected on the prenatal array sample
DNA extraction of the maternal blood sample used for maternal cell contamination testing
Testing Algorithm
This test can only be ordered on the parents when a prenatal microarray test has been ordered on the fetal sample.
This test code contains no charge and serves as a way to correlate proband and parental specimens. If additional testing is warranted, the appropriate tests will be added.
When prenatal microarray analysis is ordered, parental blood samples are collected and prepared for confirmation studies should an abnormality be detected on the prenatal sample. If an abnormality is detected on the fetal sample, the most appropriate testing (microarray, FISH, or chromosome analysis) to aid in the interpretation of the prenatal result is performed on the parental samples. A paternal blood sample is desired but not required.
Maternal cell contamination testing will be performed on the maternal blood and prenatal samples to rule out the presence of maternal cells in the fetal sample.
Method Name
DNA Extraction and Cell Culture
Reporting Name
Parental Prenatal Array Prep TestSpecimen Type
VariesA whole blood EDTA and a whole blood sodium heparin specimen, as well as the reason for referral, are required.
Note: Include the name listed on the prenatal sample that was submitted for prenatal microarray analysis.
Specimen Type: Whole blood
Container/Tube: Green top (sodium heparin) and lavender top (EDTA)
Specimen Volume: 3 mL for each tube
Collection Instructions:
1. Invert several times to mix
blood.
2. Send specimens in original tubes.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Ambient (preferred) | |
| Refrigerated | ||
Clinical Information
In order to interpret equivocal array results on a prenatal sample (amniotic fluid or chorionic villus), parental studies are performed to determine if the abnormality detected on the prenatal array is inherited or de novo.
Maternal cell contamination testing is performed on the maternal blood and prenatal sample to detect the presence of maternal cells in the fetal sample.
Reference Values
An interpretive report will be provided.
Cautions
No significant cautionary statements
Day(s) Performed
Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m. to 5 p.m. CST.
Report Available
VariesPerforming Laboratory
Mayo Medical Laboratories in Rochester
CPT Code Information
This test code contains no charge and serves as a way to correlate proband parental specimens. If additional testing is warranted, the appropriate tests will be added.