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HelpTest ID PSPTG Phosphatidylserine/Prothrombin Antibody, IgG, Serum
Ordering Guidance
Cardiolipin and beta-2 glycoprotein testing are the first-tier test options for most patients. Phosphatidylserine/prothrombin antibodies are considered part of the second-tier workup.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reporting Name
PS/PT Ab, IgG, SSpecimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Report Available
2 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PSPTG | PS/PT Ab, IgG, S | 85359-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| PSPTG | PS/PT Ab, IgG, S | 85359-8 |
Useful For
Detecting IgG antibodies against phosphatidylserine/prothrombin complex in patients with strong suspicion of antiphospholipid syndrome (APS) who are negative for the APS criteria laboratory tests (lupus anticoagulant, IgG and IgM anticardiolipin/beta 2-glycoprotein I and anti-beta 2-glycoprotein I antibodies)
May be useful for the evaluation of patients with prior positive lupus anticoagulant results who are on direct oral anticoagulant therapy
May be useful as a risk marker for thrombosis in antiphospholipid antibody carriers
Day(s) Performed
Wednesday
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86148
Specimen Minimum Volume
0.4 mL
Reference Values
<18 years: Not established
≥18 years:
Negative ≤30.0 U
Borderline 30.1-40.0 U
Positive ≥40.1 U