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HelpTest ID PTU Protein, Total, 24 Hour, Urine
Useful For
Evaluation of renal disease
Screening for monoclonal gammopathy
Special Instructions
Method Name
Dye Binding (Pyrogallol Red)
Reporting Name
Protein, Total, USpecimen Type
UrineContainer/Tube: Plastic, 5-mL tube (Supply T465)
Specimen Volume: 5 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. No preservative.
Additional Information:
1. 24-Hour volume is required.
2. See Urine Preservatives in Special Instructions for multiple collections.
Urine Preservative Collection Options
|
Ambient |
Yes |
|
Refrigerated |
Preferred |
|
Frozen |
Yes |
|
6N HCl |
No |
|
50% Acetic Acid |
No |
|
Na2CO3 |
No |
|
Toluene |
Yes |
|
6N HNO3 |
No |
|
Boric Acid |
Yes |
|
Thymol |
Yes |
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 7 days |
| Frozen | 14 days | |
| Ambient | 7 days |
Clinical Information
Protein in urine is normally composed of a combination of plasma-derived proteins that have been filtered by glomeruli and have not been reabsorbed by the proximal tubules and proteins secreted by renal tubules or other accessory glands.
Increased amounts of protein in the urine may be due to:
-Glomerular proteinuria: caused by defects in permselectivity of the glomerular filtration barrier to plasma proteins (eg, glomerulonephritis or nephrotic syndrome)
-Tubular proteinuria: caused by incomplete tubular reabsorption of proteins (eg, interstitial nephritis)
-Overflow proteinuria: caused by increased plasma concentration of proteins(s) (eg, multiple myeloma, myoglobinuria)
-Urinary tract inflammation or tumor
Reference Values
<167 mg/24 hours
Reference values have not been established for patients <18 years of age.
Reference values have not been established for patients >83 years of age.
Reference value applies to 24-hour collection.
Cautions
Increased urine protein levels (false positives) may be due to contamination of urine with menstrual blood, prostatic secretions, or semen.
Protein electrophoresis and immunofixation may be required to characterize and interpret the proteinuria.
Day(s) Performed
Monday through Sunday; Continuously
Report Available
Same day/1 dayPerforming Laboratory
Mayo Medical Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
84156