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HelpTest ID RAT11 Oxalate/Creatinine Ratio, Urine
Specimen Required
Only orderable as part of a profile. For more information see ROXUR / Oxalate, Random, Urine.
Secondary ID
606751Useful For
Calculating the oxalate concentration per creatinine
Method Name
Only orderable as part of a profile. For more information see ROXUR / Oxalate, Random, Urine.
Calculation
Reporting Name
Oxalate/Creatinine RatioSpecimen Type
UrineSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 14 days |
| Frozen | 14 days | |
| Ambient | 72 hours |
Clinical Information
Oxalate is an end product of glyoxalate and glycerate metabolism. Humans have no enzyme capable of degrading oxalate so it must be eliminated by the kidney.
In tubular fluid, oxalate can combine with calcium to form calcium oxalate stones. In addition, high concentrations of oxalate may be toxic for renal cells.
Increased urinary oxalate excretion results from inherited enzyme deficiencies (primary hyperoxaluria), gastrointestinal disorders associated with fat malabsorption (secondary hyperoxaluria), or increased oral intake of oxalate-rich foods or vitamin C.
Since increased urinary oxalate excretion promotes calcium oxalate stone formation, various strategies are employed to lower oxalate excretion.
Reference Values
Only orderable as part of a profile. For more information see ROXUR / Oxalate, Random, Urine.
No established reference values.
Cautions
Ingestion of ascorbic acid (>2 g/day) may falsely elevate the measured urinary oxalate excretion.
Day(s) Performed
Monday through Saturday
Report Available
3 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester