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HelpTest ID RMPU Monoclonal Protein Studies, Random, Urine
Ordering Guidance
The use of a random urine specimen is sufficient for identifying the presence or absence of monoclonal proteins, but a 24-hour specimen is preferred for quantitating and monitoring the abnormality. See SMPU / Monoclonal Protein Studies, 24 Hour, Urine.
Shipping Instructions
Send refrigerated.
Specimen Required
Supplies: Urine Container, 60 mL (T313)
Submission Container/Tube: Plastic, 60-mL urine bottle
Specimen Volume: 50 mL
Collection Instructions:
1. Collect a random urine specimen.
2. Aliquot between 30 mL and 50 mL of urine into a plastic, 60-mL urine bottle and refrigerate.
Reporting Name
M-protein Studies, Random, USpecimen Type
UrineSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 14 days |
| Frozen | 5 days | |
| Ambient | 24 hours |
Report Available
4 to 6 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| RMPU | M-protein Studies, Random, U | 101909-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 607975 | Albumin | 6942-7 |
| 617119 | M-protein Isotype MS, Random, U | In Process |
| PTCN1 | Protein, Total, Random, U | 2888-6 |
| 617120 | Flag M-protein Isotype MS, Random, U | No LOINC Needed |
| CRTR1 | Creatinine, Random, U | 2161-8 |
| 607976 | Alpha-1 globulin | 9734-5 |
| 607977 | Alpha-2 globulin | 38190-5 |
| PCRT1 | Protein/Creatinine Ratio | 2890-2 |
| 607978 | Beta globulin | 9744-4 |
| 607979 | Gamma globulin | 9745-1 |
| 33044 | A/G Ratio | 44293-9 |
| 33045 | M spike | 40661-1 |
| 33046 | M spike | 40661-1 |
| 33047 | Impression | 49299-1 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.
Useful For
Identifying monoclonal gammopathies using random urine specimens
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84156
82570
84166
0077U
Specimen Minimum Volume
30 mL
Reference Values
CREATININE:
≥18 years old: 16-326 mg/dL
Reference values have not been established for patients younger than 18 years.
PROTEIN/CREATINE RATIO:
≥18 years: <0.18 mg/mg creatinine
Reference values have not been established for patients younger than 18 years.
ELECTROPHORESIS, PROTEIN:
The following fractions, if present, will be reported as mg/dL:
Albumin
Alpha-1 globulin
Alpha-2 globulin
Beta globulin
Gamma globulin
No reference values apply to random urines.
MASSFIX M-PROTEIN ISOTYPE:
M-protein Isotype MS:
No monoclonal protein detected
Flag M-protein Isotype MS:
Negative
Method Name
MPTRU: Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS)
RPEU: Agarose Gel Electrophoresis
RPTU2: Turbidimetry/Enzymatic Colorimetric Assay
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MPTRU | M-protein Mass-Fix, Random, U | No | Yes |
| RPEU | Protein Electrophoresis, Random, U | No | Yes |
| RPTU2 | Protein/Creatinine Ratio, Random, U | Yes, (RPTU1) | Yes |