Sign in →

Test ID RPTU Protein, Total, Random, Urine

Useful For

Evaluation of renal disease

 

Screening for monoclonal gammopathy

Method Name

Dye Binding (Pyrogallol Red)

Reporting Name

Protein, Total, Random, U

Specimen Type

Urine

Container/Tube: Plastic, 5-mL tube (Supply T465)

Specimen Volume: 4 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  14 days
  Ambient  7 days

Clinical Information

Protein in urine is normally composed of a combination of plasma-derived proteins that have been filtered by glomeruli and have not been reabsorbed by the proximal tubules and proteins secreted by renal tubules or other accessory glands.

 

Increased amounts of protein in the urine may be due to:

-Glomerular proteinuria: caused by defects in permselectivity of the glomerular filtration barrier to plasma proteins (eg, glomerulonephritis or nephrotic syndrome)

-Tubular proteinuria: caused by incomplete tubular reabsorption of proteins (eg, interstitial nephritis)

-Overflow proteinuria: caused by increased plasma concentration of proteins (eg, multiple myeloma, myoglobinuria)

Reference Values

Males <0.11 mg/mg creatinine

Reference values have not been established for male patients <18 years of age.

Reference values have not been established for male patients >83 years of age.

 

Females <0.16 mg/mg creatinine

Reference values have not been established for female patients <18 years of age.

Reference values have not been established for female patients >83 years of age.

Cautions

False-positive urine protein levels (increased) may be due to contamination of urine with menstrual blood, prostatic secretions, or semen.

 

Protein electrophoresis and immunofixation may be required to characterize and interpret the proteinuria.

Day(s) Performed

Monday through Sunday; Continuously

Report Available

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84156

NY State Approved

Yes