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HelpTest ID SPAS Arsenic Speciation, Random, Urine
Specimen Required
Patient Preparation:
1. Patient should not eat seafood for a 48-hour period prior to start of collection.
2. High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.
Supplies:
-Urine Tubes, 10 mL (T068)
-Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube: Clean, plastic urine collection container
Submission Container/Tube: Plastic vial or a clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a random urine specimen.
2. See Metals Analysis Specimen Collection and Transport for complete instructions.
Useful For
Diagnosing arsenic intoxication using random urine specimens
Special Instructions
Method Name
Triple-Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)/Ion Chromatography Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name
Arsenic Speciation, Random, USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 72 hours |
Reference Values
TOXIC ARSENIC
<35 mcg/L
Reference values apply to all ages.
Arsenic Speciation Interpretive Information:
The toxic arsenic concentration represents the sum of the inorganic and methylated arsenic species. The reference value for toxic arsenic is <35 mcg/L. This value is based on the ACGIH Biological Exposure Index (BEI), which does not include the nontoxic organic arsenic.
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SPAS | Arsenic Speciation, Random, U | 54454-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 607692 | Inorganic Arsenic (Toxic) | 12481-8 |
| 607693 | Methylated Arsenic (Toxic) | 53779-5 |
| 607694 | Organic Arsenic (Non-Toxic) | 53778-7 |
| 609405 | Toxic Arsenic Concentration | 96250-6 |
| 607691 | Total Arsenic Concentration | 5586-3 |
CPT Code Information
82175
Testing Algorithm
Total arsenic will be performed first. If the total arsenic concentration is 10 mcg/L or greater, then speciation will be performed and reported. If total arsenic is below 10 mcg/L, total arsenic will be reported as less than 10 mcg/L and speciation will not be performed.